JOURNAL ARTICLE

Glucocorticoid Treatment Association with Intensive Care Unit Acquired Hypernatremia in Septic Shock Patients.

  • Published In: QJM: An International Journal of Medicine, 2024, v. 117. P. ii11 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Mazrou, Ayat Mohammed; Wahba, Sherif Samir; Wahba, Ramy Monier; Gad, Ehab Ahmed 3 of 3

Abstract

This article focuses on the association between glucocorticoid treatment and intensive care unit (ICU)-acquired hypernatremia in patients with septic shock. In a prospective cohort study of 120 septic shock patients treated with low-dose corticosteroids at Ain Shams University hospitals, 43.33% developed ICU-acquired hypernatremia, which was significantly linked to longer steroid administration (over seven days), mechanical ventilation, and acute kidney injury. The study found that prolonged corticosteroid use correlates with increased hypernatremia, longer ICU stays, and higher mortality, highlighting the need for careful serum sodium monitoring during glucocorticoid therapy in critically ill patients.

Additional Information

  • Source:QJM: An International Journal of Medicine. 2024/10, Vol. 117, pii11
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:1460-2725
  • DOI:10.1093/qjmed/hcae175.024
  • Accession Number:181635645
  • Copyright Statement:Copyright of QJM: An International Journal of Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Looking to go deeper into this topic? Look for more articles on EBSCOhost.