JOURNAL ARTICLE

Identification of Risk Factors and Development of Prediction Models for Glasgow Coma Scale Score Deterioration in Stroke Patients: A Study Based on the MIMIC-IV Database.

  • Published In: Journal of Intensive Care Medicine, 2025, v. 40, n. 9. P. 937 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Fan, Xuehui; Xu, Jing; Ye, Ruixue; Zhao, Jingpu; Wang, Yulong 3 of 3

Abstract

This article focuses on identifying risk factors associated with Glasgow Coma Scale (GCS) deterioration in stroke patients using data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. The study analyzed 1,984 adult patients with various stroke subtypes and found that higher Sequential Organ Failure Assessment (SOFA) scores, older age, and increased minimum anion gap levels significantly predicted GCS deterioration during hospitalization. Subgroup analyses revealed that risk factors varied across stroke types, highlighting the importance of individualized clinical management. These findings suggest that monitoring organ dysfunction, metabolic disturbances, and patient age can aid early identification of high-risk patients and inform tailored treatment strategies to improve neurocritical care outcomes.

Additional Information

  • Source:Journal of Intensive Care Medicine. 2025/09, Vol. 40, Issue 9, p937
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:0885-0666
  • DOI:10.1177/08850666251325788
  • Accession Number:186372275
  • Copyright Statement:Copyright of Journal of Intensive Care Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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