JOURNAL ARTICLE

Detection of extensive host–virus DNA hybrids in human polyomavirus 7-associated pruritic rash.

  • Published In: British Journal of Dermatology, 2023, v. 188, n. 5. P. 675 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Starrett, Gabriel J; Lee, Jae W; Chatterjee, Subhajit; Jedrych, Jaroslaw J 3 of 3

Abstract

Further investigation of host-virus junctions in the DNA-Seq identified 35 929 unique junctions nonoverlapping with those observed in the RNA-Seq, suggesting low clonality and transcriptional activation of these DNAs. The viral genome (NC 014407) had 37.7 million aligned reads (> 750 000 × coverage) from DNA sequencing (DNA-Seq) and 3.1 million aligned reads from total RNA sequencing (RNA-Seq). Https://doi.org/10.1093/bjd/ljad002 Dear Editor, Human polyomavirus 7 (HPyV7) is associated with pruritic dermatoses that occur in immunocompromised patients. [Extracted from the article]

Additional Information

  • Source:British Journal of Dermatology. 2023/05, Vol. 188, Issue 5, p675
  • Document Type:Article
  • Subject Area:History
  • Publication Date:2023
  • ISSN:0007-0963
  • DOI:10.1093/bjd/ljad002
  • Accession Number:163912436
  • Copyright Statement:Copyright of British Journal of Dermatology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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