JOURNAL ARTICLE

Catalytic Enantioselective [4+2] Cycloadditions of Salicylaldehyde Acetals with Enol Ethers.

  • Published In: Angewandte Chemie International Edition, 2024, v. 63, n. 4. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Hu, Xiaojun; Zhu, Zhengbo; Li, Zhongzheng; Adili, Alafate; Odagi, Minami; Abboud, Khalil A.; Seidel, Daniel 3 of 3

Abstract

A readily accessible conjugate‐base‐stabilized carboxylic acid (CBSCA) catalyst facilitates highly enantioselective [4+2] cycloaddition reactions of salicylaldehyde‐derived acetals and cyclic enol ethers, resulting in the formation of polycyclic chromanes with oxygenation in the 2‐ and 4‐positions. Stereochemically more complex products can be obtained from racemic enol ethers. Spirocyclic products are also accessible. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Angewandte Chemie International Edition. 2024/01, Vol. 63, Issue 4, p1
  • Document Type:Article
  • Subject Area:History
  • Publication Date:2024
  • ISSN:1433-7851
  • DOI:10.1002/anie.202315759
  • Accession Number:174782091
  • Copyright Statement:Copyright of Angewandte Chemie International Edition is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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