Augmented prehabilitation – is there a role for glucocorticoids and/or anabolic steroids to improve surgical outcomes?

The article discusses the potential role of glucocorticoids and anabolic steroids in improving surgical outcomes through augmented prehabilitation. Surgery is a major treatment option for cancer, but postoperative complications can lead to increased mortality and hinder access to adjuvant therapy. Prehabilitation strategies, such as exercise and nutrition interventions, have been shown to reduce complications and improve patient well-being. However, not all patients respond to prehabilitation, and factors such as inflammation and anabolic resistance may contribute to this. The use of glucocorticoids and anabolic steroids as part of prehabilitation regimens is being explored to enhance the response to prehabilitation and improve surgical outcomes. However, the safety and efficacy of these drugs in surgical and cancer patients need further investigation. [Extracted from the article]