JOURNAL ARTICLE

Human Disease due to Mycobacterium bovis Linked to Free-Ranging Deer in Michigan.

  • Published In: Clinical Infectious Diseases, 2024, v. 78, n. 3. P. 637 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Sunstrum, James; Power, Laura E; Fligiel, Helene M; Lauter, Carl; Kawam, Rayanah; Dado, Christopher; Weatherhead, Matthew; Denbesten, Karen; Bott, Jonathan; Cinti, Sandro; Maxwell, Daniel; Signs, Kimberly; Stobierski, Mary Grace; Cosgrove, Melinda; Moriarty, Megan; Vanderklok, Michael; Meyerson, Joshua; Thacker, Tyler; Robbe-Austerman, Suelee 3 of 3

Abstract

This article focuses on the ongoing zoonotic transmission of Mycobacterium bovis, a cause of tuberculosis (TB), from free-ranging white-tailed deer to humans and cattle in northern lower Michigan, identified as a unique enzootic focus since 1994. Between 2019 and 2022, four additional human cases linked to this wildlife reservoir were confirmed using whole genome sequencing (WGS), demonstrating close molecular relationships among M. bovis isolates from humans, deer, and cattle. The cases included pulmonary and cutaneous disease, with some involving immunosuppressed individuals and documented human-to-human transmission. The report emphasizes the need for a One Health approach integrating human, veterinary, and environmental health sectors to improve screening, public education, and transmission mitigation in this region.

Additional Information

  • Source:Clinical Infectious Diseases. 2024/03, Vol. 78, Issue 3, p637
  • Document Type:Article
  • Subject Area:Life Sciences
  • Publication Date:2024
  • ISSN:1058-4838
  • DOI:10.1093/cid/ciae009
  • Accession Number:176151698
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