JOURNAL ARTICLE

Association between β-carotene supplementation and risk of cancer: a meta-analysis of randomized controlled trials.

  • Published In: Nutrition Reviews, 2023, v. 81, n. 9. P. 1118 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Zhang, Yulin; Yang, Jiaqi; Na, Xiaona; Zhao, Ai 3 of 3

Abstract

This article focuses on a meta-analysis of randomized controlled trials (RCTs) examining the association between supplemental β-carotene intake and cancer risk. The analysis of 18 studies involving over 80,000 participants found no significant effect of β-carotene supplementation on overall cancer incidence but identified a significant increase in lung cancer risk, particularly among smokers and those receiving low-dose β-carotene supplements. No significant associations were observed for other site-specific cancers. The findings suggest that β-carotene supplementation is not recommended for cancer prevention, especially in smokers, and highlight the need to establish a tolerable upper intake level for β-carotene.

Additional Information

  • Source:Nutrition Reviews. 2023/09, Vol. 81, Issue 9, p1118
  • Document Type:Article
  • Subject Area:Nutrition and Dietetics
  • Publication Date:2023
  • ISSN:0029-6643
  • DOI:10.1093/nutrit/nuac110
  • Accession Number:169973857
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