JOURNAL ARTICLE

Impact of a calcium replacement protocol during massive transfusion in trauma patients at a level 2 trauma center.

  • Published In: American Journal of Health-System Pharmacy, 2024, v. 81. P. S160 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Shandaliy, Yana; Busey, Kirsten; Scaturo, Nicholas 3 of 3

Abstract

This article evaluates the impact of a standardized calcium replacement protocol on reducing hypocalcemia in adult trauma patients undergoing massive transfusion protocols (MTPs) at a single level 2 trauma center. The retrospective pre-post study found that implementation of the protocol significantly decreased the incidence of hypocalcemia (ionized calcium <1.1 mg/dL) within 24 hours of MTP initiation (63% postprotocol vs. 95.2% preprotocol) and shortened the time to first calcium dose. Although adherence to the protocol was limited (37%), no increase in adverse events or mortality was observed. The findings suggest that proactive, protocolized calcium administration during MTP may improve calcium homeostasis in hemorrhaging trauma patients, warranting consideration of such protocols in trauma resuscitation practices.

Additional Information

  • Source:American Journal of Health-System Pharmacy. 2024/09, Vol. 81, pS160
  • Document Type:Article
  • Subject Area:Nutrition and Dietetics
  • Publication Date:2024
  • ISSN:1079-2082
  • DOI:10.1093/ajhp/zxae099
  • Accession Number:179145806
  • Copyright Statement:Copyright of American Journal of Health-System Pharmacy is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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