JOURNAL ARTICLE

Findings on Neuropsychopharmacology Detailed by Researchers at Kobe University Graduate School of Medicine (Japanese Cohort Study Identifies an Association Between the Serotonin Transporter-Linked Polymorphic Region and Suicide Death).

  • Published In: Psychology & Psychiatry Journal, 2026. P. 1605 1 of 2

  • Database: Psychology Source 2 of 2

Abstract

This article focuses on research investigating the association between the serotonin-transporter-linked polymorphic region (5-HTTLPR) of the SLC6A4 gene and suicide death in a Japanese population. The study analyzed genetic data from 448 suicide decedents and 361 controls, finding significant differences in 5-HTTLPR genotype and allele distributions, with the S allele linked to increased suicide risk. Although subgroup and matched analyses supported these findings, a broader meta-analysis did not confirm a significant association. The research suggests a potential biological factor in suicide risk related to serotonin regulation, emphasizing the need for further studies in larger and more diverse populations. [Extracted from the article]

Additional Information

  • Source:Psychology & Psychiatry Journal. 2026/05, p1605
  • Document Type:Article
  • Subject Area:Pharmacy and Pharmacology
  • Publication Date:2026
  • ISSN:1944-2718
  • Accession Number:193210775
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