JOURNAL ARTICLE

Seoul National University School of Dentistry Reports Findings in Phenothiazine Antipsychotics (The antipsychotic chlorpromazine reduces neuroinflammation by inhibiting microglial voltage-gated potassium channels).

  • Published In: Psychology & Psychiatry Journal, 2024. P. 509 1 of 2

  • Database: Psychology Source 2 of 2

Abstract

A study conducted by Seoul National University School of Dentistry in South Korea found that the antipsychotic chlorpromazine can reduce neuroinflammation by inhibiting microglial voltage-gated potassium channels. The research suggests that chlorpromazine acts as a microglial Kv1.3 channel inhibitor and neuroinflammation modulator, potentially offering therapeutic benefits for neuroinflammatory psychiatric and neurological disorders. The study was supported by the National Research Foundation of Korea and has been peer-reviewed, providing valuable insights into the potential mechanisms of action for chlorpromazine in treating neuroinflammation. [Extracted from the article]

Additional Information

  • Source:Psychology & Psychiatry Journal. 2024/11, p509
  • Document Type:Article
  • Subject Area:Pharmacy and Pharmacology
  • Publication Date:2024
  • ISSN:1944-2718
  • Accession Number:180598799
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