SYNTHESIS OF LIF:MG,TI NANOPARTICLES BY CO-PRECIPITATION METHOD AND EVALUATION OF INCREASING THE 5A/5 RATIO IN ALPHA AND GAMMA RADIATION.

This article focuses on the synthesis and characterization of lithium fluoride doped with magnesium and titanium (LiF:Mg,Ti) thermoluminescence nanopowders for enhanced nanodosimetry applications. The study investigates how variations in ingredient concentration, stirring time, reaction temperature, and surfactant addition affect nanoparticle size, shape, and thermoluminescence properties, particularly the intensity ratio of peak 5a to peak 5 in the glow curve. Results show that smaller nanoparticles with regular geometric shapes, especially those synthesized under optimized conditions and irradiated with high linear energy transfer (LET) alpha particles or high doses of gamma radiation, exhibit a significant increase in the 5a/5 ratio without altering standard readout methods. This ratio is important for estimating energy deposition at nanoscale distances relevant to DNA damage, suggesting these nanopowders offer a practical, cost-effective tool for nanodosimetry and potentially for assessing radiation-induced DNA double-strand breaks.