JOURNAL ARTICLE

Simultaneous Determination of the Content of Isoimperatorin, Imperatorin, Oxypeucedanin, Xanthotoxol and Byakangelicin in Angelica dahurica by HPTLC Scanning.

  • Published In: Journal of Chromatographic Science, 2023, v. 61, n. 8. P. 717 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Yang, Hanting; Li, Qian 3 of 3

Abstract

This article focuses on establishing a rapid, simple, and low-cost high-performance thin-layer chromatography (HPTLC) method for determining five coumarin components—isoimperatorin, imperatorin, oxypeucedanin, xanthotoxol, and byakangelicin—in Angelica dahurica, a traditional Chinese medicinal herb. Using solvent extraction and optimized mobile phase conditions (petroleum ether-ethyl acetate, 3:2 v/v), the method achieved good separation, precision, repeatability, and recovery, with results validated by nuclear magnetic resonance (NMR) spectroscopy. The study highlights HPTLC as an effective alternative to more complex and costly chromatographic techniques for quality control and authenticity verification of A. dahurica in traditional Chinese medicine.

Additional Information

  • Source:Journal of Chromatographic Science. 2023/09, Vol. 61, Issue 8, p717
  • Document Type:Article
  • Subject Area:Politics and Government
  • Publication Date:2023
  • ISSN:0021-9665
  • DOI:10.1093/chromsci/bmac087
  • Accession Number:172443399
  • Copyright Statement:Copyright of Journal of Chromatographic Science is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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