JOURNAL ARTICLE

Revaccination for Hepatitis B in Previous Nonresponders Following Hepatitis C Eradication.

  • Published In: Journal of Infectious Diseases, 2024, v. 229, n. 2. P. 341 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Powell, Jesse G; Goble, Spencer R; Debes, Jose D 3 of 3

Abstract

This article focuses on the efficacy of hepatitis B virus (HBV) revaccination in patients who were previously nonresponsive to HBV vaccination and subsequently achieved hepatitis C virus (HCV) eradication. In a prospective study of 34 patients with chronic HCV who failed to develop hepatitis B surface antibody (HBsAb) after initial HBV vaccination, 67.7% showed a reactive HBsAb following revaccination after successful HCV treatment. The study found no significant differences in vaccine response related to age, sex, race, advanced liver fibrosis, HIV coinfection, or dialysis status. These findings suggest that revaccination for HBV after HCV cure may improve immune response in prior nonresponders, supporting consideration of revaccination timing in this population.

Additional Information

  • Source:Journal of Infectious Diseases. 2024/02, Vol. 229, Issue 2, p341
  • Document Type:Article
  • Subject Area:Politics and Government
  • Publication Date:2024
  • ISSN:0022-1899
  • DOI:10.1093/infdis/jiad301
  • Accession Number:175465696
  • Copyright Statement:Copyright of Journal of Infectious Diseases is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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