JOURNAL ARTICLE

A - 110 Cognitive Phenotypes in Children with a History of Brain Tumors.

  • Published In: Archives of Clinical Neuropsychology, 2023, v. 38, n. 7. P. 1282 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Robinson, Mary L; Bean, Akanksha M; Schneider, Bruna M; Krapf, Erica M; Hassara, Kathleen E 3 of 3

Abstract

The article focuses on identifying cognitive phenotypes in children with a history of pediatric brain tumors (PBTs) to understand latent cognitive profiles and the influence of clinical and sociodemographic factors. Using k-means clustering on neuropsychological test scores from 67 children aged 8–17, two distinct cognitive clusters were found, with one group showing multi-domain impairments linked to infratentorial tumor location, history of hydrocephalus, and exposure to multiple treatment modalities (surgery, radiation, chemotherapy). Other factors such as age at diagnosis, time since treatment, tumor grade, seizures, and genetic diagnoses did not differentiate the clusters. The study suggests the need for larger, more diverse samples and additional variables to develop generalizable cognitive phenotype models in this population.

Additional Information

  • Source:Archives of Clinical Neuropsychology. 2023/10, Vol. 38, Issue 7, p1282
  • Document Type:Abstract
  • Subject Area:Psychology
  • Publication Date:2023
  • ISSN:0887-6177
  • DOI:10.1093/arclin/acad067.127
  • Accession Number:174274905
  • Copyright Statement:Copyright of Archives of Clinical Neuropsychology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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