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Exploring The Nipah Virus: Insights Into Pathogenesis And Therapeutic Approaches.

  • Published In: Cuestiones de Fisioterapia, 2024, v. 53, n. 3. P. 1678 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: V., Divya; V., Aparna; M., Lakshmy; K., Anu.; V. R., Sunitha 3 of 3

Abstract

Nipah virus (NiV), classified as a biosafety level-4 (BSL-4) pathogen, poses a significant challenge in the field of infectious diseases, as its capacity to move between animals and humans raises serious global health concerns. This analysis explores the historical progression of NiV outbreaks, examining its effects on communities globally. This study investigates the emergence and epidemiology of the virus, focussing on its transmission dynamics and the significant impact it has had on affected regions. The neurological sequelae observed in survivors highlight the critical need for thorough care strategies. The exploration of molecular targets for antiviral drug development and current vaccine initiatives is undertaken, in conjunction with computational strategies in drug design. Targeting Ephrin-B2 and Ephrin-B3 presents a promising approach in NiV therapeutics, providing specificity and the potential for broad-spectrum activity. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Cuestiones de Fisioterapia. 2024/09, Vol. 53, Issue 3, p1678
  • Document Type:Article
  • Subject Area:Science
  • Publication Date:2024
  • ISSN:1135-8599
  • Accession Number:186654486
  • Copyright Statement:Copyright of Cuestiones de Fisioterapia is the property of Cuestiones de Fisioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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