JOURNAL ARTICLE

Assessment of antimicrobial resistant bacteria and antimicrobial resistance genes in hospital, pharmaceutical and agricultural settings in Lagos state, Nigeria.

  • Published In: Minerva Biotechnology & Biomolecular Research, 2025, v. 37, n. 3. P. 123 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: AJAYI, Abraham; CHUKWU, Emelda; ESSIET, Utibeima U.; YISAU, Jacob; OSUOLALE, Kazeem; ABUBAKAR, Rufai; EZEOBI, Paschal; OKWUZU, Jane; ADEWALE, Babatunde; SALAKO, Babatunde; OYETIBO, Ganiyu O.; TO BUN, Yewande A.; ADEOTI, Saheed T.; MACAULAY, Rasheed; OMILEYE, Ayokunle; YUSUF, Rashidat; SHEPPARD, Samuel K.; IGUMBOR, Ehimario U.; Fagoonee, Sharmila; SMITH, Stella I. 3 of 3

Abstract

The article focuses on assessing antimicrobial resistant bacteria (ARB) and antimicrobial resistance genes (ARGs) in hospital, pharmaceutical, and agricultural environments in Lagos State, Nigeria. Wastewater and soil samples from a tertiary hospital, pharmaceutical company, abattoir, and livestock farms were analyzed, revealing physicochemical parameters exceeding recommended limits and the presence of multiple bacterial species, notably Klebsiella pneumoniae and Enterobacter spp., with significant resistance to antibiotics such as pefloxacin, trimethoprim/sulfamethoxazole, and ciprofloxacin. The blaTEM resistance gene was detected in all samples, while blaCMY and qnrS genes were also prevalent, indicating widespread dissemination of ARGs across these environments. The study highlights these effluents as hotspots for antibiotic resistance spread, emphasizing the need for improved waste treatment, responsible antibiotic use, and integrated surveillance under a One Health framework to mitigate public health risks.

Additional Information

  • Source:Minerva Biotechnology & Biomolecular Research. 2025/09, Vol. 37, Issue 3, p123
  • Document Type:Article
  • Subject Area:Science
  • Publication Date:2025
  • ISSN:2724-542X
  • DOI:10.23736/S2724-542X.25.03229-8
  • Accession Number:188376955
  • Copyright Statement:Copyright of Minerva Biotechnology & Biomolecular Research is the property of Edizioni Minerva Medica and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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