Effect of Silver Content and T4 Treatment on the In Vitro Degradation Behavior of Gasar Porous Mg–Ag Alloy.

Mg–Ag alloy has potential as a material for bone tissue repair, but the faster degradation rate in vivo limits its use in medical applications. In this study, pure Mg and Mg99.5Ag0.5 alloy with a porous structure are prepared using the metal/gas eutectic unidirectional solidification method (Gasar process). The influence of introducing Ag on the degradation behavior of porous Mg99.5Ag0.5 and pure Mg is investigated. The addition of Ag increases the compressive strength and elastic modulus of the material. The corrosion resistance of as‐cast Mg99.5Ag0.5 alloy decreases due to localized aggregation of Ag in the alloys. Therefore, the T4 (solution treatment) is chosen for the Mg99.5Ag0.5 alloy. After T4 treatment, due to the uniform distribution of Ag atoms in the alloy, the corrosion behavior on the alloy surface is more uniform, and a denser Mg(OH)2 passivation layer is formed on the surface, which reduces the degradation rate of Mg99.5Ag0.5. Importantly, insoluble Ca–P compounds in the form of hydroxyapatite (HA) phases gradually grown on passivated layers of porous T4 Mg99.5Ag0.5 contribute to bone growth. This indicates the feasibility of using the T4 Gasar porous Mg99.5Ag0.5 alloy as a potential tissue engineering scaffold. [ABSTRACT FROM AUTHOR]