Numerical and computational fluid dynamics experimental analysis of novel extended tetra-hybrid Tiwari and Das Sisko nanofluid passed a stenosed artery.

The medical industry extensively uses nanoparticles for applications such as wound dressing, artificial organ components, drug delivery, tissue engineering, and cardiovascular disease treatment. The incorporation of nanoparticles into the base fluid enhances the rate of heat transmission and additionally decreases blood pressure. This study aims to examine the effects of a new tetra-hybrid nanofluid model, which includes nanoparticles, on the flow of blood through a stenosed artery with a circular shape. Model partial differential equations (PDEs) incorporate phenomena such as thermal radiation and viscous dissipation. Furthermore, we transform these modeled PDEs into dimensionless ordinary differential equations (ODEs) using self-similarity variables and numerically solve the proposed ODEs using the well-established Lobatto IIIa numerical technique. The impact of several dimensionless parameters on the heat transfer rate, skin friction, velocity, and temperature fields has been computed and analyzed using figures and tables. Moreover, we conducted a computational fluid dynamics (CFD) investigation on a tetra-hybrid nanofluid, using blood as the base fluid. The results indicate that heat transmission is higher in tetra-hybrid nanoparticles compared to tri-hybrid and di-hybrid nanofluids. The volume fraction of nanoparticles in the base fluid increases, resulting in a decrease in the surface drag coefficient and a decrease in the heat transport phenomenon. Amplification in the thermal radiation parameter improves heat transfer, helping to remove toxins and plaque from blood flowing through arteries. An increase in thermal radiation generates excess heat that dilates inflexible arteries, facilitating blood flow. From CFD analysis, it is observed that thermal conduction k and heat transfer coefficient h amplify by improving Reynolds number. Pressure at the outlet interface of the tube decreases from 3058 Pa to 2996 Pa for the case of a 10% volume fraction of nanoparticles. Velocity boundary layer thickness decreases from 1.46 to 1.37 with an increase in the volume fraction of nanoparticles from 1% to 10%. Heat deliverance rate amplifies in the case of tetrahybrid nanofluid 2.5394–2.6147 in contrast to trihybrid nanofluid 2.4008 to 2.4711 by amplifying Rd from 0.7 to 1.1. The surface drag coefficient amplifies by magnifying Re but the Nusselt number diminishes by improving the volume fraction of nanoparticles. [ABSTRACT FROM AUTHOR]