Trajectories of Objective Sleep Quality and Their Association With Neurological Functional Recovery After Stroke: A Prospective Longitudinal Study.

This study focuses on identifying latent trajectory classes of objective sleep quality in stroke patients and examining their impact on neurological functional recovery over 12 months. Using ActiGraph GT3X+ triaxial accelerometers, four distinct sleep quality trajectories were identified among 306 patients: consistently good sleep quality, short sleep with improving efficiency and fragmentation, long sleep with reduced efficiency and worsening fragmentation, and consistently poor sleep quality. Patients in the long sleep-reduced efficiency-deteriorated fragmentation group and consistently poor sleep quality group exhibited significantly higher risks—5.7 and 6.8 times respectively—of poor neurological recovery compared to those with consistently good sleep quality. The findings highlight the heterogeneity of post-stroke sleep patterns and suggest that personalized sleep management should be integrated into stroke rehabilitation to potentially improve functional outcomes.