Indigenous underrepresentation in American and Canadian atopic dermatitis clinical trials: a 10-year cross-sectional analysis.

  • Published In: Clinical & Experimental Dermatology, 2025, v. 50, n. 5. P. 1017 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Akuffo-Addo, Edgar; Boisvert, Jeannie; Asiniwasis, Rachel 3 of 3

Abstract

The article focuses on the underrepresentation of Indigenous peoples in clinical trials for atopic dermatitis (AD) in the United States and Canada. It highlights that Indigenous populations experience higher prevalence and severity of AD, influenced by social and environmental determinants of health, yet only 0.91% of participants in the analyzed trials were Indigenous. The research examined 61 completed trials over a 10-year period, revealing systemic barriers to participation, including historical mistrust and limited access to trial sites. The authors emphasize the need for cultural sensitivity and community engagement to improve Indigenous representation in clinical research. [Extracted from the article]

Additional Information

  • Source:Clinical & Experimental Dermatology. 2025/05, Vol. 50, Issue 5, p1017
  • Document Type:Article
  • Subject Area:Social Sciences and Humanities
  • Publication Date:2025
  • ISSN:0307-6938
  • DOI:10.1093/ced/llae426
  • Accession Number:185321473
  • Copyright Statement:Copyright of Clinical & Experimental Dermatology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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