IMPACT OF MULTIPLE PESTICIDE EXPOSURES ON CHILDHOOD CANCER RISK IN AGRICULTURAL COMMUNITIES. A COMPREHENSIVE EPIDEMIOLOGICAL STUDY.

Environmental exposures, particularly pesticides, are more and more a cause for concern in the incidence of childhood cancer. This comprehensive epidemiological study investigates the impact of multiple pesticide exposures on childhood cancer risk in agricultural communities. We use pesticide application records, bio monitoring data from a large cohort of high exposure children and cancer registry information for both leukemia and brain and lymphoma cancer types in order to investigate associations between cumulative exposures and specific cancer types. Such potential confounders like socioeconomic status, genetic predisposition, as well as environmental toxins are controlled through advanced statistical models. What we found is that there are very significant correlations between pesticides, and increased risk of childhood cancer, and that is why it indicates that stricter regulatory policies, and more safety, indeed are necessary. This study emphasises the dire need for early life exposure ameliorating targets for mitigating early life exposures and of reducing early life exposure early in early life. These results add to the accumulating evidence on environmental determinants of pediatric cancer and gain insight in public health strategies in agricultural regions. [ABSTRACT FROM AUTHOR]