Neuroplasticity in the Biopsychosocial Framework: A Foundational Theory for Intervention.

This article focuses on integrating the concept of neuroplasticity—the brain's ability to change structurally and functionally in response to experiences—within Engel's biopsychosocial (BPS) framework to enhance social work research and practice. The BPS framework emphasizes the transactional interplay among biological, psychological, and sociocultural factors influencing an individual, aligning with social work's person-in-environment approach. The authors propose a conceptual model that situates neuroplasticity within this framework, highlighting its relevance to understanding and treating depression by linking environmental stressors, brain changes, and mental health outcomes. While acknowledging limitations and concerns about reductionism, the article advocates for incorporating neuroscience knowledge into social work education and interventions to address mental health holistically and promote social justice.