COMPARATIVE CLINICAL EVALUATION OF EFFICACY OF BIODENTINE AND BROMELAIN WITH BIODENTINE AS DIRECT PULP CAPPING MATERIALS.

Objectives: This study aimed to evaluate the efficacy of Biodentine and a combination of bromelain with Biodentine as direct pulp capping materials. Methods: This clinical study included 26 participants with mature permanent mandibular molars exhibiting deep carious lesions without pulpal exposure. The participants were divided into two groups: Group I received Biodentine alone, while Group II received a combination of bromelain and Biodentine. Clinical and radiographic follow-ups were performed at 1, 3, and 6 months to assess the success rates of the treatment modalities. Results: The clinical success rate of Biodentine as a direct pulp capping agent was 92% at 1 month, 100% at 3 months, and 92% at 6 months follow-up. The radiographic success rate was 100% at all intervals. The clinical success rate of the bromelain with Biodentine group was 85% at 1 month, 91% at 3 months, and 100% at 6 months, with corresponding radiographic success rates of 92%, 91%, and 100% at the respective intervals. Statistical analysis revealed no significant difference in success rates between the two groups. Conclusions: Both Biodentine and the combination of bromelain with Biodentine demonstrated high clinical and radiographic success rates in direct pulp capping. However, there was no statistically significant difference between the two groups, suggesting that bromelain may not provide additional benefits when combined with Biodentine. Further research with larger sample sizes and longer follow-up periods is needed to explore the potential of bromelain and other combinations for direct pulp capping. These findings contribute to our understanding of effective materials for vital pulp therapy and guide clinical decision-making in dental practice. [ABSTRACT FROM AUTHOR]