Effects of digital technology-based serious games interventions for older adults with mild cognitive impairment: a meta-analysis of randomised controlled trials.

This article systematically reviews and meta-analyzes the effectiveness of digital technology-based serious games (DTBSGs) interventions in older adults with mild cognitive impairment (MCI). Based on 28 randomized controlled trials involving 1,698 participants, DTBSGs showed moderate-quality evidence for improving global cognitive function and activities of daily living (ADL), and low-quality evidence for enhancing executive function, attention, and reducing depression, but no significant effects on memory, anxiety, apathy, or quality of life. Subgroup analyses indicated that computer games, exergames, and iPad tablet games were more effective than immersive virtual reality (VR) games for global cognitive and executive functions, while VR games were superior for attention and ADL. The study highlights DTBSGs as promising adjuncts or alternatives to traditional rehabilitation for MCI, while noting the need for standardized methodologies and further research on long-term efficacy and integration into healthcare systems.